… of models is most predictive of clinical treatment efficacy. … role of our in vitro time kill-kinetics
assay as an asset to a predictive preclinical modeling framework assessing anti-tuberculosis …

… In vitro time kill-kinetics assays can be adopted in a predictive preclinical modelling
framework to assess anti-tuberculosis drug activity. This provides important information on the …

… Therefore, as described in this paper, time-kill kinetics assays … The role of the time-kill
kinetics assay as part of a preclinical … of anti-tuberculosis drugs. Tuberculosis (Edinb) 105:80–85. …

… of assessing and reporting PKPD of anti-tuberculosis drugs when … the extent of the drug
by performing time-kill kinetic studies, … pre-clinical models are useful in the tuberculosis drug …

… The role of the time-kill kinetics assay as part of a preclinical modeling framework for
assessing the activity of anti-tuberculosis drugs. Tuberculosis (Edinb) 105:80–85. …

… and verapamil to evaluate their potentiating capacity. … drugs in preclinical models [19,20].
Its capacity to inhibit … at which the time-kill kinetics assays were performed (Section 2.6.). On …

… For rapid anti-tuberculosis (TB) drug development in vitro … the related mathematical modeling
approaches of time–kill data. … to quantify in humans, preclinical models in animals and in …

… A study for the investigation of the importance of an in vitro time kill-kinetics assay as an …
preclinical modeling framework evaluating the activity of anti-tuberculosis drugs used this assay. …

… The role of the time-kill kinetics assay as part of a preclinical modeling framework for
assessing the activity of anti-tuberculosis drugs. Tuberculosis. 2017;105:80–5. …

… In this study, we evaluate the effect of … the time-kill kinetics of the two drugs alone and
in combination against M. bovis BCG strain. Kill kinetics is an important asset of the pre-clinical …